Senior Scientist I / II, Drug Delivery Modeling & Simulation

Company: AbbVie
Location: Irvine
Posted on: December 31, 2025

Job Description:

Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok . Job Description As Senior Scientist I or II in AbbVie Drug Delivery Sciences, you will work as a key part of a talented, multidisciplinary, and cross-functional team to build cutting-edge capabilities for the delivery of biologics and small molecules and advance new products through early R&D. We are seeking a highly motivated PhD Chemical Engineer specializing in the modeling and simulation of drug release kinetics in advanced drug delivery systems. The successful candidate will apply first-principles understanding to design, optimize, and analyze drug delivery platforms, utilizing quantitative models to predict and control drug release profiles. Responsibilities: Develop and apply mechanistic models for drug release kinetics from various sustained drug delivery platforms (e.g., in situ forming depots, implants, hydrogels, etc.,). Employ first-principles approaches (e.g., diffusion, convection, chemical reaction theories) to solve complex transport problems relevant to drug delivery formulations. Design, execute, and analyze computational simulations using tools such as COMSOL Multiphysics or similar platforms. Collaborate with formulation and material scientists, and pharmacologists, to translate modeling results into experimental design and product development. Interpret experimental release data and integrate findings into enhanced models for predictive accuracy. Communicate findings through technical reports, publications, and presentations Qualifications PhD in Chemical Engineering Senior Scientist I: PhD with 0 - 4 years of relevant experience (industry, post-docs, or academia). Senior Scientist II: PhD with 4 years of relevant industry experience. Strong foundation in mass transport phenomena (diffusion, dissolution, convection, degradation). Demonstrated expertise in mathematical modeling and simulation of controlled release mechanisms. Proficiency in relevant modeling and simulation software (COMSOL Multiphysics, Monte Carlo methods or equivalent) Excellent problem-solving, quantitative, and communication skills. Ability to work collaboratively in a multidisciplinary environment. Prior experience with drug delivery system design and evaluation is preferred. Leadership Competencies: Deals comfortably with risk and ambiguity, changing course when needed. Lives AbbVie values. Acts consistently with our ethics, obligations, and the law. Acts respectfully yet courageously. Communicates openly and honestly with all colleagues. Look outside AbbVie for new ideas to stimulate innovation. Connects unrelated concepts, generates original or unique ideas. Persistent and resilient - finds the way to move good ideas forward. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: This is an on-site opportunity located in AbbVie's Irvine, CA location. The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. This job is eligible to participate in our long-term incentiveprograms Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

Keywords: AbbVie, Compton , Senior Scientist I / II, Drug Delivery Modeling & Simulation, Science, Research & Development , Irvine, California